| Introduction |
Pharmacokinetics Made Easy 1R presents the complex subject of pharmacokinetics in a simple, easy-to-understand manner, lending itself to a wide audience including medical practitioners, health professionals and students of pharmacology, medicine and nursing. The physiological approach adopted in the book allows clinical issues in drug therapy to be addressed, making it directly applicable to practice situations. The chapters in this book were initially published as a series of articles in Australian Prescriber to assist practitioners in drug dosing and therapy. In this revised edition, the book has been updated according to recent developments and a new chapter called 'How to Determine the Pharmacokinetic Parameters of a Drug' added. Each chapter also has a new feature-a list of key points summarising the content to improve accessibility and understanding. |
| Description |
Pharmacokinetics Made Easy 1R presents the complex subject of pharmacokinetics in a simple, easy-to-understand manner, lending itself to a wide audience including medical practitioners, health professionals and students of pharmacology, medicine and nursing. The physiological approach adopted in the book allows clinical issues in drug therapy to be addressed, making it directly applicable to practice situations. The chapters in this book were initially published as a series of articles in Australian Prescriber to assist practitioners in drug dosing and therapy. In this revised edition, the book has been updated according to recent developments and a new chapter called 'How to Determine the Pharmacokinetic Parameters of a Drug' added. Each chapter also has a new feature-a list of key points summarising the content to improve accessibility and understanding. |
| Key Features |
A glossary of symbols and of important pharmacokinetic relationships Equations to describe the physiological factors underlying important pharmacokinetic processes.
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| Table of Contents |
Preface About the authors Definitions and Units of Symbols Equations Introduction 1. Clearance 2. Volume of Distribution 3. Half-life 4. How Drugs are Cleared by the Liver 5. Bioavailability and First-Pass Clearance 6. Predicting Drug Interactions and the Effects of Disease States for Metabolised Drugs 7. Clearance of Drugs by the Kidneys 8. Drug Protein Binding 9. Non-Linear Pharmacokinetics 10. How to Determine the Pharmacokinetic Parameters of a Drug 11. Pharmacodynamics-the Concentration-Effect Relationship 12. Designing Dose Regimens 13. Therapeutics Drug Monitoring Answers |
